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How can scientists update coronavirus vaccines for omicron? A microbiologist answers FIVE (5) questions about how Moderna and Pfizer could ‘Rapidly Adjust’ mRNA vaccines

Ezekiel 33:2-6

“”When I bring the sword upon a land, and the people of the land take a man from their territory and make him their watchman,

3, when he sees the sword coming upon the land, if he blows the trumpet and warns the people,

4, then whoever hears the sound of the trumpet and does not take warning, if the sword comes and takes him away, his blood shall be on his own head.

5, He heard the sound of the trumpet, but did not take warning; his blood shall be upon himself. But he who takes warning will save his life.

6, But if the watchman sees the sword coming and does not blow the trumpet, and the people are not warned, and the sword comes and takes any person from among them, he is taken away in his iniquity; but his blood I will require at the watchman”s hand.” (Ezekiel 33:2-6)

Revelation 19:20 

And the beast was taken, and with him the false prophet that wrought miracles before him, with which he deceived them that had received the mark of the beast, and them that worshipped his image. These both were cast alive into a lake of fire burning with brimstone.

Revelation 14:11

And the smoke of their torment ascendeth up for ever and ever: and they have no rest day nor night, who worship the beast and his image, and whosoever receiveth the mark of his name.

Pastor Mike Taylor;

Each of us are watchmen on the wall. If you stand behind a pulpit or preach to a congregation in whatever media you use, you have a responsibility to warn those who are in danger of hell fire and all that it represents. God does not send anyone to hell, as it is a decision that each of us must make, but the Word of God must start with men and women who are commissioned by God to take the Word of Truth to those who are in their sins.

Whether a minister believes he is a watchman or not, he is commissioned by God to spread the Gospel to the lost. He is to preach the penalty of sin. He is to abandon a feel good “gospel”, prosperity gospel, or a social speech of humanism and being just a “good citizen”. This won’t save anyone. It will not warn those who are walking the wide road and gate to destruction, but will only placate them that they are OK…they are not OK, as they do not have Jesus in their hearts. It is a minister’s job to take the message of salvation to his congregation, his community and the rest of the world.

Jan Markell, Olive Tree Ministries;

Prepping for ‘Mr. Fix-It’

 Society is being prepped for the Antichrist, and as prophecy-loving believers try to warn, the words are falling on a lot of deaf ears.

 The stage is being set for a closing act. The players are getting into their proper positions. Heads of state are meeting to plot and scheme and deny even more rights. In places like Australia, Lithuania, and Austria, good people are enemies of the state even though they are upstanding citizens.

 World leaders have no comprehension they are majoring in minors. To them, it makes perfect sense to obsess over carbon emissions. During the Tribulation, this will fade from their memories as they cope with Seals and Trumpets and Bowls. These will spark “climate change” they cannot imagine!

 Most receiving this newsletter are “watchmen.” Ezekiel 33 tells us that if you don’t warn, the blood is on your hands, so you cannot be silent.

 Brace yourself to be shocked daily by things you read and watch. Satan is getting more active, and wickedness is rising, so God’s people must shine more brightly.

 But for the believer, a glorious event will happen soon. It is known as the Rapture of the Church. It is any day. Any hour. Any minute. So don’t grow weary!

 And yes, if a believer is a Rapture skeptic, they get the surprise of their life someday soon. Then you’ll have the privilege of saying, “I told you so.”

 Won’t that be a glorious day?

Pastor Greg Laurie; Harvest Ministries

“God promises this in the book of Revelation, and He also gives us a promise of global peace. The Antichrist, however, will bring pseudo peace. During the first three-and-a-half years of the seven-year Tribulation, he will come across as a good guy. But in reality, he will be a bad guy. And the Scriptures say that he will use peace to deceive many. Ultimately, once Antichrist is taken out of the way, God will bring global peace.”

Paul Rolland, Night Watchman, Night Watchman Ministries

Matthew 24:37 But as the days of Noah were, so shall also the coming of the Son of man be.

Genesis 6:9, 11, 12 These are the generations of Noah: Noah was a just man and perfect in his generations, and Noah walked with God. The earth also was corrupt before God, and the earth was filled with violence. And God looked upon the earth, and, behold, it was corrupt; for all flesh had corrupted his way upon the earth.

Genesis 7:1-4  And the Lord said unto Noah, Come thou and all thy house into the ark; for thee have I seen righteous before me in this generation. Of every clean beast thou shalt take to thee by sevens, the male and his female: and of beasts that are not clean by two, the male and his female. Of fowls also of the air by sevens, the male and the female; to keep seed alive upon the face of all the earth. For yet seven days, and I will cause it to rain upon the earth forty days and forty nights; and every living substance that I have made will I destroy from off the face of the earth.

How can scientists update coronavirus vaccines for omicron? A microbiologist answers FIVE (5) questions about how Moderna and Pfizer could rapidly adjust mRNA vaccines

December 2, 2021 5.03pm EST The Conversation

If the omicron variant of the coronavirus is different enough from the original variant, it’s possible that existing vaccines won’t be as effective as they have been. If so, it’s likely that companies will need to update their vaccines to better fight omicron. Deborah Fuller is a microbiologist who has been studying mRNA and DNA vaccines for over two decades. Here she explains why vaccines might need to be updated and what that process would look like.

1. Why might vaccines need to be updated?

Basically, it’s a question of whether a virus has changed enough so that antibodies created by the original vaccine are no longer able to recognize and fend off the new mutated variant.

Coronaviruses use spike proteins to attach to ACE-2 receptors on the surface of human cells and infect them. All mRNA COVID-19 vaccines work by giving instructions in the form of mRNA that direct cells to make a harmless version of the spike protein. This spike protein then induces the human body to produce antibodies. If a person is then ever exposed to the coronavirus, these antibodies bind to the coronavirus’s spike protein and thus interfere with its ability to infect that person’s cells.

The omicron variant contains a new pattern of mutations to its spike protein. These changes could disrupt the ability of some – but probably not all – of the antibodies induced by the current vaccines to bind to the spike protein. If that happens, the vaccines could be less effective at preventing people from getting infected by and transmitting the omicron variant.

2. How would a new vaccine be different?

Existing mRNA vaccines, like those made by Moderna or Pfizer, code for a spike protein from the original strain of coronavirus. In a new or updated vaccine, the mRNA instructions would encode for the omicron spike protein.

By swapping out the genetic code of original spike protein for the one from this new variant, a new vaccine would induce antibodies that more effectively bind the omicron virus and prevent it from infecting cells.

People already vaccinated or previously exposed to COVID-19 would likely need only a single booster dose of a new vaccine to be protected not only from the new strain but also other strains that may be still in circulation. If omicron emerges as the dominant strain over delta, then those who are unvaccinated would only need to receive 2-3 doses of the updated vaccine. If delta and omicron are both in circulation, people would likely get a combination of the current and updated vaccines.

3. How do scientists update a vaccine?

To make an updated mRNA vaccine, you need two ingredients: the genetic sequence of the spike protein from a new variant of concern and a DNA template that would be used to build the mRNA.

In most organisms, DNA provides the instructions for making mRNA. Since researchers have already published the genetic code for the omicron spike protein, all that’s left to do is make a DNA template for the spike protein that would be used to produce the mRNA part of new vaccines.

To do this, researchers mix DNA templates with synthetic enzymes and four molecular building blocks that make mRNA – G, A, U and C for short. The enzymes then build an mRNA copy of the DNA template, a process called transcription. Using this process, it takes only minutes to produce a batch of the mRNA for vaccines. Researchers then place the mRNA transcripts within fatty nanoparticles that protect the instructions until they are safely delivered into cells in your arm.

4. How long until a new vaccine might be ready?

It takes only three ‘3’ days to generate the DNA template needed to make a new mRNA vaccine. Then it would take about a week to produce sufficient doses of the mRNA vaccine for testing in the lab and another six ‘6’ weeks to perform the pre-clinical tests on human cells in test tubes to make sure a new vaccine works as it should.

So within 50 (5) days, scientists could have an updated mRNA vaccine ready to plug into the manufacturing process and begin producing doses for a human clinical trial. That trial would likely require at least another few weeks for a total of around 100 days to update and test a new vaccine.

While that trial is going on, manufacturers could start switching their current process to making a new vaccine. Ideally, once the clinical trial is complete – and if the vaccine gets authorized or approved – a company could immediately start rolling out doses of a new vaccine.

5. Does an updated vaccine need full clinical trials?

It’s currently not clear how much clinical data would be required to get FDA approval or authorization for an updated COVID-19 vaccine. However, all the ingredients would be the same in a new vaccine. The only difference would be a few lines of genetic code that would ever so slightly change the shape of the spike protein. From a safety perspective, an updated vaccine is essentially identical to the already tested vaccines. Because of these similarities, clinical testing may not need to be as extensive as what was needed for the first-generation COVID-19 vaccines.

At a minimum, clinical trials for updated vaccines would likely require safety testing and confirmation that an updated vaccine induces antibody levels on par with the response of the original vaccine against the original, beta and delta strains. If these are the only requirements, then researchers would enroll only hundreds – not tens of thousands – of people to obtain the clinical data needed.

One important thing to note is that if vaccine manufacturers decide to update their vaccines for the omicron variant, it wouldn’t be their first time making this kind of change.

A previous variant, B.1.351, emerged in October 2020 and was sufficiently resistant to then-current vaccines to warrant updating them. Manufacturers quickly responded to the potential threat by developing an updated mRNA vaccine to match this variant and performed clinical trials to test the new vaccine. Fortunately, this variant did not become the dominant variant. But if it had, vaccine manufacturers would have been ready to roll out an updated vaccine.

If it turns out that omicron – or any future variant, for that matter – warrants a new vaccine, companies have already completed the ‘dress rehearsals’ and are ready to meet the challenge.

8 References to ‘BE WATCHING or WATCHFUL.’ ‘8’ indicates that a new ‘era or epoch’ is arriving. Be it the rapture, the tribulation, the year of the Jews redemption or the year of the onset (2028) of the 1000 year millennial reign of Christ (2028-3028).

Matthew 24:42; Watch therefore: for ye know not what hour your Lord doth come.

Matthew 25:13; Watch therefore, for ye know neither the day nor the hour wherein the Son of man cometh.

Mark 13:35; Watch ye therefore: for ye know not when the master of the house cometh, at even, or at midnight, or at the cockcrowing, or in the morning.

Luke 21:36; Watch ye therefore, and pray always, that ye may be accounted worthy to escape all these things that shall come to pass, and to stand before the Son of man

Luke 12:37-39; Blessed are those servants, whom the lord when he cometh shall find watching: verily I say unto you, that he shall gird himself, and make them to sit down to meat, and will come forth and serve them. And if he shall come in the second watch, or come in the third watch, and find them so, blessed are those servants. And this know, that if the goodman of the house had known what hour the thief would come, he would have watched, and not have suffered his house to be broken through.

 ‘Increasing Like Labor Pains.’ ‘Fearful Sights.’ ‘Perilous Times.’ ‘Men’s hearts failing with fear.’ Great Convergence of Signs.’ REDEMPTION IMMINENT.

In His Service,

Night Watchman

Paul Rolland

Night Watchman Ministries

Make Your Decision for Christ NOW!!!!!!! Time is Up!!!!!!!

Jesus Christ’s Offer of Salvation:

The ABCs of Salvation through Jesus Christ (the Lamb)

A. Admit/Acknowledge/Accept that you are sinner. Ask God’s forgiveness and repent of your sins.

. . . “For all have sinned, and come short of the glory of God.” (Romans 3:23).

. . . “As it is written, There is none righteous, no, not one.” (Romans 3:10).

. . . “If we say that we have no sin, we deceive ourselves, and the truth is not in us.” (1 John 1:8).

B. Believe Jesus is Lord. Believe that Jesus Christ is who He claimed to be; that He was both fully God and fully man and that we are saved through His death, burial, and resurrection. Put your trust in Him as your only hope of salvation. Become a son or daughter of God by receiving Christ.

. . . “That whosoever believeth in him should not perish, but have eternal life. For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life. For God sent not his son into the world to condemn the world; but that the world through him might be saved. (John 3:15-17). For whosoever shall call upon the name of the Lord shall be saved.” (Romans 10:13).

C. Call upon His name, Confess with your heart and with your lips that Jesus is your Lord and Savior.

. . . “That if thou shalt confess with thy mouth the Lord Jesus, and shalt believe in thine heart that God hath raised him from the dead, thou shalt be saved. For with the heart man believeth unto righteousness; and with the mouth confession is made unto salvation.” (Romans 10:9-10).

. . . “If we say that we have no sin, we deceive ourselves, and the truth is not in us. If we confess our sins, he is faithful and just to forgive us our sins, and to cleanse us from all unrighteousness. If we say that we have not sinned, we make him a liar, and his word is not in us.” (John 1:8-10).

. . . “And he is the propitiation for our sins: and not for ours only, but also for the sins of the whole world. (John 2:2).

. . . “In this was manifested the love of god toward us, because that God sent his only begotten Son into the world, that we might live through him. And we have seen and do testify that the Father sent the Son to be the Saviour of the world. Whosoever shall confess that Jesus is the Son of God, God dwelleth in him, and he in God.” (1 John 4:9, 14-15).

. . . “But God commendeth his love toward us, in that, while we were yet sinners, Christ died for us. Much more then, being now justified by his blood, we shall be saved from wrath through him. For if, when we were enemies, we were reconciled to God by the death of his Son, much more, being reconciled, we shall be saved by his life.” (Romans 5:8-10).

. . . “For the wages of sin is death; but the gift of God is eternal life through Jesus Christ our Lord.” (Romans 6:23).

. . . “Jesus saith unto them, I am the way, the truth, and the life, no man cometh unto the Father, but by me.” (John 14:6).

. . . “For I am not ashamed of the gospel of Christ: for it is the power of God unto salvation to everyone that believeth.” (Romans 1:16).

. . . “Neither is there salvation in any other: for there is none other name under heaven given among men, whereby we must be saved.” (Acts: 4:12).

. . . “Who will have all men to be saved, and to come unto the knowledge of the truth for there is one God, and one mediator between God and men, the man Christ Jesus.” (1 Timothy 2:4-6).

. . . “For God did not appoint us to suffer wrath but to receive salvation through our Lord Jesus Christ.” (1 Thessalonians 5:9).

. . . “But as many as received him, to them gave the power to become the sons of God, even to them that believe on his name.” (John 1:12).

True Church / Bride of Christ Spared from God’s Wrath:

 Romans 5:8-10. “But God commendeth his love toward us, in that, while we were yet sinners, Christ died for us. Much more then, being now justified by his blood, we shall be saved from wrath through him. For if, when we were enemies, we were reconciled to God by the death of his Son, much more, being reconciled, we shall be saved by his life.”

Romans 12:19. Dearly beloved, avenge not yourselves, but rather give place unto wrath: for it is written, Vengeance is mine; I will repay, saith the Lord.

1 Thessalonians 1:10. And to wait for his Son from heaven, whom he raised from the dead, even Jesus, which delivered us from the wrath to come.

1 Thessalonians 5:9. For God hath not appointed us to wrath, but to obtain salvation by our Lord Jesus Christ,

Romans 8:35. Who shall separate us from the love of Christ? shall tribulation, or distress, or persecution, or famine, or nakedness, or peril, or sword?

Jeremiah 30:7. Alas! for that day is great, so that none is like it: it is even the time of Jacob’s trouble, but he shall be saved out of it.

Revelation 3:10 Because thou hast kept the word of my patience, I also will keep thee from the hour of temptation, which shall come upon all the world, to try them that dwell upon the earth.

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