CHINESE SCIENTISTS SAY THEY’VE FOUND A SAFER ALTERNATIVE TO CRISPR GENE EDITING
JULY 19TH 19__KRISTIN HOUSER. futurism.com
Researchers from China’s Peking University have developed a new gene-editing technology — and they think it shows promise as a CRISPR alternative for fighting human diseases.
According to a paper published on Monday in the journal Nature Biotechnology, this new technology, LEAPER, which stands for “leveraging endogenous ADAR for programmable editing of RNA,” works similarly to CRISPR-Cas13, targeting RNA molecules as opposed to DNA like the well-known CRISPR-Cas9.
But while CRISPR-Cas13 relies on both a guide RNA and the Cas13 enzyme to make its edits to RNA, the LEAPER system needs just one component known as an arRNA. This makes the system “more easily deliverable and less likely to result in unwanted cellular immune responses,” the researchers told China-based media outlet Caixin.
As for the potential uses of their CRISPR alternative, Peking researcher Zhou Zhuo told Caixin that “there are clear prospects for using this technology in disease treatment.”
In fact, in tests of cells taken from people with the debilitating genetic disorder Hurler syndrome, LEAPER was able to correct “sufficient amounts” of the cells’ mutated RNA, University of Queensland geneticist Ernst Wolvetang, who wasn’t involved in the research, told Caixin.
However, the research is still in the early stages and is only now moving into tests on animals — meaning we won’t know for some time if LEAPER will dethrone CRISPR as the preeminent gene-editing technology.
Matthew 24:37 But as the days of Noah were, so shall also the coming of the Son of man be.
Genesis 6:9, 11, 12 These are the generations of Noah: Noah was a just man and perfect in his generations, and Noah walked with God. The earth also was corrupt before God, and the earth was filled with violence. And God looked upon the earth, and, behold, it was corrupt; for all flesh had corrupted his way upon the earth.
Genesis 7:1-4 And the Lord said unto Noah, Come thou and all thy house into the ark; for thee have I seen righteous before me in this generation. Of every clean beast thou shalt take to thee by sevens, the male and his female: and of beasts that are not clean by two, the male and his female. Of fowls also of the air by sevens, the male and the female; to keep seed alive upon the face of all the earth. For yet seven days, and I will cause it to rain upon the earth forty days and forty nights; and every living substance that I have made will I destroy from off the face of the earth.
Genetic Manipulation
Genetic Sequencing
Genome Mapping
Genetic Splicing
Genetic Alteration
Genetic Cutting
CRISPR
LEAPER
Genetic Editing
Genetic Chimeras
Genetic Abominations
Genetic Corruption of Flesh
DNA
Chimeras
Hybrids
Nephilim
Germline Editing
Categories: Genetic Manipulation and Hybridization Update
