Blog note: As in the days of Noah. All flesh was corrupted. Only Noah was perfect in his generation (not genetic corruption). End of note.
Congrats on the new baby. Want to screen your baby’s DNA? Part Two in a Series.
By Susan Scutti, CNN. Updated 9:23 AM ET, Sun January 6, 2019
How is a baby’s genome sequenced?
“The first genome was sequenced in 2003 and cost $3 billion to do,” Lantos recalled. Today, sequencing is “a combination of computer applications and people,” he explained.
First, a genome machine “spits out” the millions of base pairs of an individual genome, said Lantos. Next, a computer program sifts through these pairs and boils them down to a subset. This “preliminary cut” might show a 100 genetic mutations that appear to be disease-causing, 19,000 that look harmless and 1,000 mutatations of unknown significance, he said.
For the last step in the process, a trained genetic scientist looks at that result and does an analysis “that is more art than science,” said Lantos.
It’s only become technically feasible to do full-scale sequencing studies, including the several infant studies sponsored by the NIH, in the last five years, he said: “The question is, can we develop a way to use this innovation that does more good than harm?”
Categories: Genetic Manipulation and Hybridization Update