'Last' 'Latter' 'End of' Days

Genetic Manipulation: Lucifers Attempt At Perverting the ‘Seed’ (Genetics) Of Man For 6,000 Years. Breakthrough: Artificial DNA opens door to designer proteins. Saudi Prince Plans City With Human Gene Editing. Researchers are getting closer to creating human embryos with DNA from two men. New research has revealed that it may one day be possible for a male couple to create a biological child together.

Lucifer’s Attempt to Pervert the Seed of Man – Dr. Larry Ollison

Satan’s Corruption of Genetics ‘Seed’ in the World:

Genesis 6 When human beings began to increase in number on the earth and daughters were born to them, the sons of God [the ‘Watchers’, ‘Fallen Angels’, ‘Sons of Disobediance’] saw that the daughters of humans were beautiful, and they married any of them they choseThen the Lord said, “My Spirit will not contend with humans forever, for they are mortal; their days will be a hundred and twenty years.”

The Nephilim were on the earth in those days—and also afterward—when the sons of God went to the daughters of humans and had children by them. They were the heroes of old, men of renown.

What (7) were the ‘days of Noah’ like? ALL (7) FLESH HAD BECOME CORRUPTED, DEFILED OR ‘UNCLEAN’.

Matthew 24:37 But as the days (7) of Noah were, so shall also the (7) coming of the Son of man be.

Genesis 6:9, 11, 12 (7) These are the generations of Noah: Noah (7) was a just man and perfect in (7) his generations, and Noah walked with God. (7) The earth also was corrupt before God, (7) and the earth was filled with violence. (7) And God looked upon the earth, and, (7) behold, it was corrupt; for all flesh (7) had corrupted his way upon the earth.

(77777777) 8×7. Eight (‘8’) is God’s Divine Number denoting a ‘change’ in time, season, periods, stage, epoch or millennium. In this case, God is declaring that man’kind had been genetically ‘changed, corrupted or ‘unclean’, and that the ‘genetic corruption’ on Earth had to wiped out (Great Flood), and then restarted or ‘restocked’ with clean genetics (to keep ‘seed alive’ on the Earth.) Similar to ‘culling’ infected livestock and replacing them with ‘clean’ livestock. Plain and Simple.

Genesis 7:1-4  And the Lord said unto (7) Noah, Come thou and all thy house (7) into the ark; for thee have I (7) seen righteous before me in this generation. Of every (7) clean beast thou shalt take to thee (7) by sevens, the male and his female: and of (7) beasts that are not clean by two, the (7) male and his female. Of fowls also (7) of the air by sevens, the male (7) and the female; to keep seed alive (7) upon the face of all the earth. For yet (7) seven days, and I will cause it (7) to rain upon the earth forty days (7) and forty nights; and every living substance (7) that I have made will I destroy (7) from off the face of the earth. (77777+77777+77777) 15×7

Center for the Fourth Industrial Revolution Kingdom of Saudi Arabia (C4IR KSA)

Saudi Prince Plans City With Human Gene Editing

Futurism: (Article Excerpts)

Neom sounds like something straight out of a science-fiction novel.

Buried in the 2,300 pages of planning documents obtained by the WSJ are plans for the forcible relocation of local tribes, the creation of human gene-editing clinics, and 24/7 government surveillance — meaning this futuristic city may be more like dystopian sci-fi than the fun Jetsons kind. Since 2017, Saudi Crown Prince Mohammed bin Salman, better known as MBS, has been working with teams of consultants to develop his vision 2030 for the $500 billion city in the currently barren northwestern corner of Saudi Arabia.

2030 Vision

It’d be easy to get distracted by all the shiny things detailed in the Neom planning documents — but the futuristic city also sounds suspiciously like a totalitarian surveillance state. “This should be an automated city where we can watch everything,” Neom’s founding board is quoted as saying in the documents, according to the WSJ. “[A city] where a computer can notify crimes without having to report them or where all citizens can be tracked.”

That means while you’re chilling on the glowing beach, daydreaming about your next prix fixe meal, a drone equipped with facial-recognition technology will likely be transmitting your location to Neom’s “1984”-esque law enforcement officials. That’ll be thanks to all the medical clinics genetically modifying Neom’s citizens to be stronger, not to mention smarter — meaning MBS might not just be planning to create the city of the future, but the humans of it as well.

2030 Vision

From CRISPR to cloning: The science of new humans | GZERO World with Ian Bremmer

Researchers are getting closer to creating human embryos with DNA from two men. New research has revealed that it may one day be possible for a male couple to create a biological child together.

Story by Molly Sprayregen LGBTQ Generation March 23, 2024

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New research has revealed that it may one day be possible for a male couple to create a biological child together.

Scientists at Oregon Health & Science University (OHSU) have been working on a process called in vitro gametogenesis (IVG), in which they create an egg from a skin cell and then fertilize it with sperm.

Military will soon cover IVF services for LGBTQ+ veterans & servicemembers

The coverage will also extend to single folks and will finally allow for the use of donated eggs, sperm, and embryos.

The researchers have been using mice for the process, which involves removing the nucleus of a skin cell and transferring it into a donated egg that has had its nucleus removed. From there, the scientists eliminate half the chromosomes in the nucleus so a sperm cell can fertilize it. A similar process was used to clone Dolly the sheep in 1996, though that did not involve removing and replacing half the chromosomes.

The study’s senior author, Shoukhrat Mitalipov, director of the OHSU Center for Embryonic Cell and Gene Therapy, and professor of obstetrics and gynecology, and molecular and cellular biosciences, in the OHSU School of Medicine, told OHSU News that the goal “is to produce eggs for patients who don’t have their own eggs.” IVG could potentially be used to assist those with uteruses experiencing infertility as well as male same-sex couples in producing biological children.The scientists are reportedly studying how it could work with human cells, and while there have been key developments, it will still be years before anything is put into practice.

“This gives us a lot of insight,” said Paula Amato, professor of obstetrics and gynecology at OHSU School of Medicine. “But there is still a lot of work that needs to be done to understand how these chromosomes pair and how they faithfully divide to actually reproduce what happens in nature.”

As of now, the chromosomes have only paired correctly in rare cases, so the next step of the research is to “determine how we enhance that pairing so each chromosome pair separates correctly,” explained Mitalipov. This study is considered unique from the way other researchers have approached IVG. Many scientists are working on a process that involves reprogramming skin cells into stem cells and then using them to create egg or sperm cells.

“We’re skipping that whole step of cell reprogramming,” said Amato. “The advantage of our technique is that it avoids the long culture time it takes to reprogram the cell. Over several months, a lot of harmful genetic and epigenetic changes can happen.”

Genetic Manipulation: Lucifers Attempt At Perverting the ‘Seed’ Genetics) Of Man For 6,000 Years.

Scientists create novel technique to form human artificial chromosomes

Story by Science X staff Phys.org March 22, 2024

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Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory applications, though serious technical obstacles have hindered their development. Now a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania has made a significant breakthrough in this field that effectively bypasses a common stumbling block.

In a study published in Science, the researchers explained how they devised an efficient technique for making HACs from single, long constructs of designer DNA. Prior methods for making HACs have been limited by the fact that the DNA constructs used to make them tend to join together—”multimerize”—in unpredictably long series and with unpredictable rearrangements.

The new method allows HACs to be crafted more quickly and precisely, which in turn will directly speed up the rate at which DNA research can be done. In time, with an effective delivery system, this technique could lead to better engineered cell therapies for diseases like cancer.

“Essentially, we did a complete overhaul of the old approach to HAC design and delivery,” said Ben Black, Ph.D., the Eldridge Reeves Johnson Foundation Professor of Biochemistry and Biophysics at Penn. “The HAC we built is very attractive for eventual deployment in biotechnology applications, for instance, where large scale genetic engineering of cells is desired. A bonus is that they exist alongside natural chromosomes without having to alter the natural chromosomes in the cell.”

The first HACs were developed 25 years ago, and artificial chromosome technology is already well advanced for the smaller, simpler chromosomes of lower organisms such as bacteria and yeast. Human chromosomes are another matter, due largely to their greater sizes and more complex centromeres, the central region where X-shaped chromosomes’ arms are joined.

Researchers have been able to get small artificial human chromosomes to form from self-linking lengths of DNA added to cells, but these lengths of DNA multimerize with unpredictable organizations and copy numbers—complicating their therapeutic or scientific use—and the resulting HACs sometimes even end up incorporating bits of natural chromosomes from their host cells, making edits to them unreliable.

In their study, the Penn Medicine researchers devised improved HACs with multiple innovations: These included larger initial DNA constructs containing larger and more complex centromeres, which allow HACs to form from single copies of these constructs. For delivery to cells, they used a yeast-cell-based delivery system capable of carrying larger cargoes.

“Instead of trying to inhibit multimerization, for example, we just bypassed the problem by increasing the size of the input DNA construct so that it naturally tended to remain in predictable single-copy form,” said Black. The researchers showed that their method was much more efficient at forming viable HACs compared to standard methods, and yielded HACs that could reproduce themselves during cell division.

The potential advantages of artificial chromosomes—assuming they can be delivered easily to cells and operate like natural chromosomes—are many. They would offer safer, more productive, and more durable platforms for expressing therapeutic genes, in contrast to virus-based gene-delivery systems which can trigger immune reactions and involve harmful viral insertion into natural chromosomes.

Normal gene expression in cells also requires many local and distant regulatory factors, which are virtually impossible to reproduce artificially outside of a chromosome-like context. Moreover, artificial chromosomes, unlike relatively cramped viral vectors, would permit the expression of large, cooperative ensembles of genes, for example to construct complex protein machines. Black expects that the same broad approach his group took in this study will be useful in making artificial chromosomes for other higher organisms, including plants for agricultural applications such as pest-resistant, high-yield crops.

Researchers from the J. Craig Venter Institute, the University of Edinburgh, and the Technical University Darmstadt were also involved in the study.

More information: Craig W. Gambogi et al, Efficient formation of single-copy human artificial chromosomes, Science (2024). DOI: 10.1126/science.adj3566

Provided by Perelman School of Medicine at the University of Pennsylvania

Breakthrough: Artificial DNA opens door to designer proteins

Story by Rizwan Choudhury Interesting Engineering 2024

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DNA, the molecule that stores the genetic information of all living things, is made up of just four chemical letters, or nucleotides. But what if we could add more letters to this alphabet and create new kinds of DNA?

That’s what a team of researchers from the University of California San Diego, the Foundation for Applied Molecular Evolution, and the Salk Institute for Biological Studies have done. They have developed a new version of DNA with six letters instead of four, showing that it can be used to make proteins, the building blocks of life. This feat, published in Nature Communications, opens doors to a future where custom-designed proteins and novel biological applications could become a reality.

Four nucleotides

DNA, the blueprint of life, encodes its instructions using just four nucleotides – adenine (A), thymine (T), guanine (G), and cytosine (C). These nucleotides pair in specific configurations, forming the iconic double helix. But what if this alphabet could be expanded? The implications are compelling, ranging from personalized medicine to revolutionary materials.

“Life on Earth is amazingly diverse with just four nucleotides, so imagine what we could do with more,” said Dong Wang, Ph.D., a professor at Skaggs School of Pharmacy and Pharmaceutical Sciences at UC San Diego and the senior author of the study.

“By expanding the genetic code, we could create new molecules that have never been seen before and explore new ways of making proteins as therapeutics.”

https://www.dcnewsnow.com/video/importance-of-dna-technology/9481914/

Wang and his colleagues used a synthetic DNA system called AEGIS, which stands for Artificially Expanded Genetic Information System. AEGIS was created by Steven A. Benner, PhD, at the Foundation for Applied Molecular Evolution, as part of a NASA-funded project investigating how life could have evolved in other planets.

Dr. Dong Wang aptly describes that adding new ‘letters’ to the genetic code expands the vocabulary of life, allowing us to write more complex narratives.” His team’s breakthrough demonstrates that cells can readily incorporate synthetic nucleotides into the DNA recipe.

Using AEGIS

AEGIS adds two new letters to the standard DNA alphabet, which consists of adenine (A), thymine (T), guanine (G), and cytosine. These letters pair up in a specific way to form the double-helix structure of DNA, which was discovered by James Watson and Francis Crick in 1953.

The new letters, Z and P, have the same shape and size as the natural ones, so they can fit into the DNA helix without disrupting its geometry. This means that the enzymes that read and copy DNA, such as RNA polymerase, can recognize and process AEGIS DNA just like natural DNA.

RNA polymerase

The key lies in ‘mimicking’ nature’s machinery. The researchers identified RNA polymerase, a key enzyme that converts DNA into RNA, which is then used to make proteins. They designed two artificial nucleotides that flawlessly mimic the geometry of natural nucleotides. RNA polymerase readily accepted these novel additions when tested, seamlessly incorporating them into transcription.

The researchers tested whether RNA polymerase from bacteria could transcribe AEGIS DNA into RNA and found that it could do so with high accuracy and efficiency.

“This is a remarkable demonstration of how robust and adaptable the biological machinery is,” said Wang. “By mimicking the natural shape of DNA, our synthetic letters can sneak in and be used to make new proteins.”

This breakthrough paves the way for exciting possibilities. Imagine designing proteins with tailor-made properties capable of precisely targeting tumors for cancer therapy or engineering bacteria to synthesize eco-friendly biofuels. The vast horizons extend beyond medicine and environmental applications to materials science and potentially even synthetic biology.

Of course, challenges remain. Optimizing the incorporation of new nucleotides, ensuring their stability within the genome, and deciphering the full potential of this expanded code are areas for further exploration. Yet, the foundation for rewriting the genetic lexicon has been laid. This discovery signifies a momentous leap in our understanding of life’s blueprint. It holds the promise of ushering in a new era of biological design, where the possibilities are limited only by our imagination.  “These new proteins could have applications in medicine, biotechnology, and bioengineering,” said Wang. “We are only scratching the surface of what we can do with artificial DNA.”

Study abstract:

Artificially Expanded Genetic Information Systems (AEGIS) add independently replicable unnatural nucleotide pairs to the natural G:C and A:T/U pairs found in native DNA, joining the unnatural pairs through alternative modes of hydrogen bonding. Whether and how AEGIS pairs are recognized and processed by multi-subunit cellular RNA polymerases (RNAPs) remains unknown. Here, we show that E. coli RNAP selectively recognizes unnatural nucleobases in a six-letter expanded genetic system.

 High-resolution cryo-EM structures of three RNAP elongation complexes containing template-substrate UBPs reveal the shared principles behind the recognition of AEGIS and natural base pairs. In these structures, RNAPs are captured in an active state, poised to perform the chemistry step. At this point, the unnatural base pair adopts a Watson-Crick geometry, and the trigger loop is folded into an active conformation, indicating that the mechanistic principles underlying recognition and incorporation of natural base pairs also apply to AEGIS unnatural base pairs.

These data validate the design philosophy of AEGIS unnatural basepairs. Further, we provide structural evidence supporting a long-standing hypothesis that pair mismatch during transcription occurs via tautomerization. Together, our work highlights the importance of Watson-Crick complementarity underlying the design principles of AEGIS base pair recognition.

60 Minutes: Mohammed bin Salman:

Is This The World’s Most Dangerous Politician:

Revelation 13:7 And it (7) was given unto him to make war (7) with the saints, and to overcome them: (5) and POWER was ‘GIVEN’ him (Prince, Beast, Antichrist) (7) over ALL kindreds, and tongues, and NATIONS. (777)

The Antichrist; ‘A King of Dark Sentences’ (political language, false agreements, deceiving covenants, lies, back-room dealing, deception, intrigue, announcements and deceiving doctrines and programs.)

MbS (Man-by-Satan) – the Great Speaker, Prince or Beast Performs Wondrously and Deceivingly

23 (7) “And in the latter time of their (7) kingdom, when the transgressors are come to (7) the full, a king of fierce countenance, (7) and understanding dark sentences, shall stand up.

24 And his power shall (7) be mighty, but not by his own (7) power: and he shall destroy wonderfully, (7) and shall prosper, and practice, and shall (7) destroy the mighty and the holy people.

25 (7) And through his policy also he shall (7) cause craft to prosper in his hand; (7) and he shall magnify himself in his (7) heart, and by peace shall destroy many: he shall also (7) stand up against the Prince of princes; (7) but he shall be broken without hand.” (Daniel 8:23-25)

(77777777777777) = 7+7 = 14 (‘sevens’)

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The Mahdi, Black Kabba, Black Stone Worship and Crop Circles. What do they all have in common?

The Imam of the Age, Imam Mahdi (as) is said to come to unite the (false Islam) believers, and mankind in general under the banner of Divine Unity and guidance, bringing in a world order that is more balanced and in tune with all the facets of human nature. It is said that he (Mahdi) will establish justice by overthrowing those who have perverted it for their own gains.

And it is said that he will usher in a period of great progress and flowering of human knowledge and potential. Prince Mohammed bin Salman because they now view Saudi Arabia — with the world’s fastest growing large economy — as a global powerhouse, based in large part upon the reforms he has instituted?

(5) The Mahdi is the Antichrist

And because of that success and others, do more and more leaders now see the crown prince as one of the most influential voices in the world? That same “the room goes instantly silent to hear the words of wisdom” is now taking place on the global stage. When Mohammed bin Salman speaks, some leaders seemingly do go silent to hear every word. Why?  The world is changing. Power is shifting. Alliances are being created or reinvented, and Saudi Arabia and the crown prince are behind much of the change. It’s time to focus on the flash. (Douglas MacKinnon, a political and communications consultant, was a writer in the White House for Presidents Ronald Reagan and George H.W. Bush)

2024: The Rise of the Beast. Mohammed bin Salman. Man-by-Satan. MbS. For Those ‘Left Behind.’

“Power tends to corrupt, and absolute power corrupts absolutely.” The logical explanation for this phenomenon is the decline in the quality of leadership and ethical standards of political institutions, even with democratic accountability. A regrettable state of affairs; world politicians lack the credibility needed to build a global system that is worth complying with and respecting. Does the world not deserve a respectable leader who can put an end to the appeasement of the masses with slogans and populist actions? “We do not want another committee, we have too many already.  What we want is a man of sufficient stature to hold the allegiance of all people, and to lift us out of the economic morass into which we are sinking. Send us such a man, and be he god or devil, we will receive him.”

WHY SAUDI KINGS ARE EXTREMELY SCARED OF IMAM MAHDI? | Islamic Lectures

The Muslim Islamic Antichrist Documentary 

Paul Rolland | Night Watchman | Night Watchman Ministries |MbS Confirms (7) the False Peace Covenant For Seven Years

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In His Service,

Night Watchman

Paul Rolland

Night Watchman Ministries

Make Your (7) Decision for Christ NOW!!!!!!! Time is Up!!!!!!!

Jesus Christ’s Offer of Salvation:

The ABCs (7) of Salvation through Jesus Christ (the Lamb)

  1. (7) Admit/Acknowledge/Accept that you are sinner. Ask (7) God’s forgiveness and repent of your sins.

. . . “For all have sinned, and come short of the glory of God.” (Romans 3:23).

. . . “As it is written, There is none righteous, no, not one.” (Romans 3:10).

. . . “If we say that we have no sin, we deceive ourselves, and the truth is not in us.” (1 John 1:8).

B. Believe Jesus is Lord. Believe that (7) Jesus Christ is who He claimed to (7) be; that He was both fully God (7) and fully man and that we are (7) saved through His death, burial, and resurrection. (7) Put your trust in Him as your (7) only hope of salvation. Become a son (7) or daughter of God by receiving Christ. (7777777) 7×7

. . . “That whosoever believeth in him should not perish, but have eternal life. For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life. For God sent not his son into the world to condemn the world; but that the world through him might be saved. (John 3:15-17). For whosoever shall call upon the name of the Lord shall be saved.” (Romans 10:13).

C. Call upon His name, Confess (7) with your heart and with your lips (7) that Jesus is your Lord and Savior.

. . . “That if thou shalt confess with thy mouth the Lord Jesus, and shalt believe in thine heart that God hath raised him from the dead, thou shalt be saved. For with the heart man believeth unto righteousness; and with the mouth confession is made unto salvation.” (Romans 10:9-10).

. . . “If we say that we have no sin, we deceive ourselves, and the truth is not in us. If we confess our sins, he is faithful and just to forgive us our sins, and to cleanse us from all unrighteousness. If we say that we have not sinned, we make him a liar, and his word is not in us.” (John 1:8-10).

. . . “And he is the propitiation for our sins: and not for ours only, but also for the sins of the whole world. (John 2:2).

. . . “In this was manifested the love of god toward us, because that God sent his only begotten Son into the world, that we might live through him. And we have seen and do testify that the Father sent the Son to be the Saviour of the world. Whosoever shall confess that Jesus is the Son of God, God dwelleth in him, and he in God.” (1 John 4:9, 14-15).

. . . “But God commendeth his love toward us, in that, while we were yet sinners, Christ died for us. Much more then, being now justified by his blood, we shall be saved from wrath through him. For if, when we were enemies, we were reconciled to God by the death of his Son, much more, being reconciled, we shall be saved by his life.” (Romans 5:8-10).

. . . “For the wages of sin is death; but the gift of God is eternal life through Jesus Christ our Lord.” (Romans 6:23).

. . . “Jesus saith unto them, I am the way, the truth, and the life, no man cometh unto the Father, but by me.” (John 14:6).

. . . “For I am not ashamed of the gospel of Christ: for it is the power of God unto salvation to everyone that believeth.” (Romans 1:16).

. . . “Neither is there salvation in any other: for there is none other name under heaven given among men, whereby we must be saved.” (Acts: 4:12).

. . . “Who will have all men to be saved, and to come unto the knowledge of the truth for there is one God, and one mediator between God and men, the man Christ Jesus.” (1 Timothy 2:4-6).

. . . “For God did not appoint us to suffer wrath but to receive salvation through our Lord Jesus Christ.” (1 Thessalonians 5:9).

. . . “But as many as received him, to them gave the power to become the sons of God, even to them that believe on his name.” (John 1:12).

True Church / Bride of Christ Spared from God’s Wrath:

 Romans 5:8-10. “But God commendeth his love toward us, in that, while we were yet sinners, Christ died for us. Much more then, being now justified by his blood, we shall be saved from wrath through him. For if, when we were enemies, we were reconciled to God by the death of his Son, much more, being reconciled, we shall be saved by his life.”

Romans 12:19. Dearly beloved, avenge not yourselves, but rather give place unto wrath: for it is written, Vengeance is mine; I will repay, saith the Lord.

1 Thessalonians 1:10. And to wait for his Son from heaven, whom he raised from the dead, even Jesus, which delivered us from the wrath to come.

1 Thessalonians 5:9. For God hath not appointed us to wrath, but to obtain salvation by our Lord Jesus Christ,

Romans 8:35. Who shall separate us from the love of Christ? shall tribulation, or distress, or persecution, or famine, or nakedness, or peril, or sword?

Jeremiah 30:7. Alas! for that day is great, so that none is like it: it is even the time of Jacob’s trouble, but he shall be saved out of it.

Revelation 3:10 Because thou hast kept the word of my patience, I also will keep thee from the hour of temptation, which shall come upon all the world, to try them that dwell upon the earth.

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